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About Nontuberculous Mycobacteria (NTM) lung infections

  • People at any age can get an NTM infection.
  • It occurs more frequently in older adults and people with other lung diseases, like bronchiectasis and chronic obstructive pulmonary disease (COPD).
  • If not treated, many NTM infections may cause damage to lung tissue.
  • An NTM infection is not contagious. It cannot be passed from human to human.
  • Treatment for NTM infections generally requires long-term use of antibiotics, often for 1 to 2 years.

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Nontuberculous mycobacteria, shortened to NTM, are a type of bacteria found in water and soil. There are more than 180 strains of NTM bacteria. Most do not cause disease except in people with a weakened immune system. You get an NTM infection when you breathe in the bacteria from misty water (for example, in a shower or hot tub) or from soil. If not treated, many people may get a worsening lung infection.

About 50,000 to 90,000 people with NTM infections in the United States have NTM lung disease. NTM lung disease is more common in older adults but can affect any age group.

NTM lung infections can become chronic and require ongoing treatment. Severe NTM lung disease can affect a person’s quality of life. Death directly related to NTM lung disease is uncommon.

NTM can get into the lungs from the environment. In most people, NTM are cleared from the lungs naturally and do not cause infection.

In some people, however, NTM infects the airways and lung tissue and causes an infection. Without treatment, many people will develop a progressive lung infection. Cough, shortness of breath, fatigue, and often weight loss are symptoms.

NTM (Nontuberculous mycobacteria) & MAC (Mycobacterium avium complex)

Nontuberculous mycobacteria (NTM) is a group of organisms that includes almost 200 species. Most NTM species do not cause infections in humans, but few a NTM species do, including:

  • Mycobacterium avium complex (MAC)
    • M. avium
    • M. intracellulare
  • Mycobacterium abscessus
  • Mycobacterium kansasii
  • Mycobacterium xenopi

MAC is the most common species of NTM that causes infections in humans, and the lungs are the most common site for infection.

Since not all NTM lung infections are treated the same, it’s important to know if MAC or another NTM organism is causing the lung infection so that the appropriate treatment is started.

Living Well with NTM

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The Living well with NTM patient guide will introduce you to Nontubercelous Mycobacteria – its causes, symptoms and risk factors; how it is diagnosed; how it is treated; and how to manage the condition to minimize its impact.

This patient education is supported by an educational grant from Insmed Incorporated. Materials for this patient education guide were contributed by NTM Info & Research.